Dental Soft-Tissue Regeneration Market: Growth, Size, Share, and Trends

Report Code MD 9222
Published in Jun, 2025, By MarketsandMarkets™
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Dental Soft-tissue Regeneration Market by Product Type (Autografts, Synthetic Biomaterials, Collagen-based Membranes), Application (Implantology, Periodontology), End User (Dental Hospitals, DSO's & Independent Clinics), Region - Global Forecast to 2030

Overview

The global dental soft-tissue regeneration market, valued at US$0.36 billion in 2024, stood at US$0.38 billion in 2025 and is projected to advance at a resilient CAGR of 6.8% from 2025 to 2030, culminating in a forecasted valuation of US$ 0.53 billion by the end of the period. The increase in periodontal diseases, advancements in regenerative materials, and the rise of dental tourism, along with improved reimbursement policies, support market growth. Rising healthcare costs, especially in developing countries, will positively affect the demand for advanced dental care treatments. The growing trend of cosmetic dentistry, which enhances oral health for aesthetic reasons, further drives market expansion. However, high treatment costs and limited access to advanced treatments in underdeveloped regions may hinder the market's growth.

Dental Soft-tissue Regeneration Market – Global Forecast and Key Opportunities to 2030

Attractive Opportunities in the Dental Soft-tissue Regeneration Market

Asia Pacific

Market growth in North America can be attributed to the rising prevalence of dental diseases and the increasing demand for minimally invasive surgeries.

The growth of this market can be attributed to the expansion of pharmaceutical manufacturing facilities, increased demand for advanced biomaterials, and the rapid growth of contract manufacturing companies.

Increasing dental tourism in emerging countries is likely to promote significant growth opportunities in the market

North America dominates the dental soft-tissue regeneration market. This market is expected to register a CAGR of 6.4% during the forecast period.

Europe is the second-largest regional market for dental regeneration materials, due to increasing investments by key players in the region.

Global Dental Soft-tissue Regeneration Market Dynamics

DRIVER: Increasing prevalence of periodontal diseases

Periodontal diseases, such as gingivitis and periodontitis, are among the most common oral health issues, impacting millions of individuals each year. If left untreated, these conditions can lead to soft-tissue damage, tooth loss, and systemic complications. This highlights the increasing need for advanced regenerative solutions and dental care.

Furthermore, growing awareness of the importance of oral health is driving the demand for effective regenerative therapies. According to the World Health Organization (WHO), oral diseases affect nearly 3.5 billion people worldwide, with periodontal disease being one of the most prevalent conditions.

The rising geriatric population also contributes to market growth. In the US, the Centers for Disease Control and Prevention (CDC) reports that nearly 47% of adults aged 30 and older experience some form of periodontal disease, and this prevalence rises to 70% among those aged 65 and older. The trend toward adopting minimally invasive procedures for periodontal regeneration, along with advancements in biomaterials, is further fueling the growth of dental soft-tissue regeneration.

RESTRAINT: Declining reimbursements for dental surgeries

The dental industry has been significantly impacted by declining reimbursement rates for periodontal treatments, creating financial barriers for both suppliers and patients. Lower reimbursement means that healthcare service providers earn less from performing dental procedures, which, in turn, reduces the funds available for investing in advanced dental care and regenerative biomaterials.

In countries like the US, Medicaid and Medicare provide minimal coverage for dental procedures, while private insurers impose strict limitations on claims. These factors hinder the adoption of new technologies and slow innovation in the dental soft-tissue regeneration market.

 

OPPORTUNITY: Growing dental tourism in developing regions

The growing popularity of dental tourism in developing regions has significantly boosted the dental soft-tissue regeneration market. These countries offer affordable yet effective dental care compared to developed nations, attracting many patients. The lower cost of treatment and shorter waiting times have led to these regions becoming sought-after destinations for dental procedures.

As a result, a large number of dental tourists and their demand for advanced treatments present appealing opportunities for manufacturers and retailers of regenerative dental materials, contributing to substantial market growth. Furthermore, both the government and private sectors in developing countries promote medical tourism, which indirectly opens up markets for manufacturers and suppliers of biomaterials, as more individuals seek dental care in these areas. Therefore, the increase in dental tourism and heightened awareness of oral health create significant opportunities in the dental soft-tissue regeneration market.

CHALLENGES: Lack of skilled professionals

A significant challenge in the treatment of dental disorders is the shortage of trained dental professionals. According to the World Health Organization, there is an estimated worldwide shortage of 1.5 million oral health professionals. In India, the Indian Dental Association reports that there are over 300 dental colleges; however, only a very small number of graduates choose to specialize in periodontology. This shortage leads to limited access to advanced dental care for conditions such as periodontitis and gingivitis, particularly in rural areas where dental services are scarce. A report published in the Journal of Periodontology indicates that nearly 70% of patients with periodontal issues do not receive timely recommended treatments due to the lack of qualified professionals. Additionally, the inadequately developed training programs at dental schools worsen the situation, restricting the workforce's ability to address the increasing prevalence of periodontal diseases. This, in turn, hinders the growth of the dental soft-tissue regeneration market.

Global Dental Soft-tissue Regeneration Market Ecosystem Analysis

The ecosystem of the dental soft-tissue regeneration market consists of various elements that define its structure, including the stakeholders involved. Key participants include manufacturers, distributors, research and product developers, regulatory bodies, and end users.

Manufacturers are organizations engaged in the complete process of research, product development, optimization, and market launch. Distributors include third-party entities and eCommerce platforms that collaborate with organizations to market these products. This ecosystem encompasses the different elements and subdivisions that make up the overall dental soft tissue regeneration market.

Dental Soft-tissue Regeneration Market Ecosytem
 

By product type, collagen-based membranes hold the largest share in the dental soft-tissue regeneration market during the forecast period.

Based on product type, the collagen-based membranes segment holds the largest share of the dental soft-tissue regeneration market during the forecast period. These membranes are crucial for restoring dental soft tissues due to their biocompatible and biodegradable properties. They facilitate tissue integration and are commonly used in guided tissue regeneration (GTR) techniques. Collagen-based membranes enhance vascularization and support soft tissue healing through the controlled release of bioactive agents that promote growth factor recruitment and cellular migration. Additionally, the development of advanced regenerative biomaterials and the increasing demand for minimally invasive surgeries have further driven the growth of the dental soft-tissue regeneration market.

By end user, the DSOs & independent clinics segment holds the largest share of the dental soft-tissue regeneration market.

The dental soft-tissue regeneration market is classified based on end user into several categories: dental hospitals, DSOs & independent clinics, as well as academic & research institutions. The market is primarily dominated by DSOs & independent clinics. This trend is driven by increasing awareness of oral health, a growing number of cases of periodontal diseases, and a rise in patients seeking treatments at healthcare facilities. Furthermore, the collaboration between DSOs and independent clinics is leading to the incorporation of advanced dental regeneration techniques across various practices. This is further fueled by the rising prevalence of periodontal diseases, heightened awareness of oral health, and increasing demand for cosmetic dentistry.

North America accounted for the largest market share of the global dental soft-tissue regeneration market.

The North American region holds the largest share of the dental soft-tissue regeneration market, largely due to its rising geriatric population. This demographic is contributing to an increase in the diagnosis of dental diseases, which in turn fuels market growth. Additionally, North America boasts a highly developed healthcare infrastructure and is home to major market players that lead in innovation and demand for dental regeneration products.

The growing prevalence of dental diseases, such as gingivitis and periodontitis, creates an increased need for advanced dental care and regenerative biomaterials. Furthermore, regulatory bodies like the Food and Drug Administration (FDA) impose strict regulations on these products to ensure their safety and effectiveness, thereby boosting market growth. This combination of factors solidifies North America's position as the dominant segment in the dental soft-tissue regeneration market.

LARGEST SHARE IN 2024
US: FASTEST-GROWING MARKET IN THE REGION
Dental Soft-tissue Regeneration Market Region

Recent Developments of Dental Soft-tissue Regeneration Market

  • In March 2024, Geistlich Pharma AG (Switzerland) acquired Brazil's Bionnovation Biomedical to expand its portfolio in regenerative dentistry and strengthen its presence in Latin America and emerging markets.
  • In March 2024, Advanced Medical Solutions Group Plc (UK) acquired Peters Surgical, a leading global provider of specialty surgical sutures, mechanical haemostasis, and internal cyanoacrylate devices to strengthens its position in tissue repair and skin closure products, including geographic expansion and cross-selling opportunities.
  • In January 2024, AbbVie Inc. (US) expanded its biologics manufacturing capacity with a USD 223 million investment in its Singapore manufacturing site.
  • In December 2023, DENTSPLY Sirona (US) launched OSSIX Agile biomaterial, a long-lasting pericardium membrane used for bone graft and tissue regeneration.

Key Market Players

KEY PLAYERS IN THE DENTAL SOFT-TISSUE REGENERATION MARKET INCLUDE

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Scope of the Report

Report Metric Details
Market size available for years 2023-2030
Base Year Considered 2024
Forecast period 2025-2030
Forecast units Value (USD Million/Billion)
Segments covered Product Type, Application, End User, and Region
Geographies covered North America (US & Canada), Europe (Germany, UK, France, Italy, Spain, and RoE), APAC (Japan, China, Australia, South Korea, India, and RoAPAC), LATAM (Brazil, Mexico, Argentina, and RoLATAM), MEA, and GCC countries

Frequently Asked Questions(FAQ)

What are the drivers of the dental soft-tissue regeneration market?

The development of advanced regenerative solutions, the growing prevalence of oral health disorders, and the rising demand for cosmetic dental procedures.

Which product type dominates the dental soft-tissue regeneration market?

The collagen-based membranes segment dominates the market.

Who are the end users of the dental soft-tissue regeneration market? Which end user is leading the market?

End users include dental hospitals, DSOs & independent clinics, and academic & research institutes. The DSOs & independent clinics segment accounted for the largest market share in 2024.

Who are the key players in the dental soft-tissue regeneration market?

Geistlich Pharma AG (Switzerland), DENTSPLY Sirona (US), Institut Straumann AG (Switzerland), Zimvie Inc. (US), Henry Schein, Inc. (US), Advanced Medical Solutions Group Plc (UK), and Envista (US).

Which region is lucrative for the dental soft-tissue regeneration market?

The North American market is expected to witness the highest growth during the forecast period.

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Table of Contents

Exclusive indicates content/data unique to MarketsandMarkets and not available with any competitors.

TITLE
PAGE NO
INTRODUCTION
12
RESEARCH METHODOLOGY
34
EXECUTIVE SUMMARY
54
PREMIUM INSIGHTS
76
MARKET OVERVIEW
87
  • 5.1 INTRODUCTION
  • 5.2 MARKET DYNAMICS
    DRIVERS
    RESTRAINTS
    OPPORTUNITIES
    CHALLENGES
  • 5.3 INDUSTRY TRENDS
  • 5.4 VALUE CHAIN ANALYSIS
  • 5.5 TECHNOLOGY ANALYSIS
    KEY TECHNOLOGIES
    - 3D BIOPRINTING
    COMPLEMENTARY TECHNOLOGIES
    - LASER – ASSISTED TECHNOLOGY
    ADJACENT TECHNOLOGIES
    - ADVANCED BIOMATERIALS
  • 5.6 PORTER'S FIVE FORCE ANALYSIS
  • 5.7 REGULATORY LANDSCAPE
    REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATION
    REGULATORY FRAMEWORK
  • 5.8 PATENT ANALYSIS
  • 5.9 TRADE ANALYSIS
  • 5.10 PRICING ANALYSIS
    AVERAGE SELLING PRICE TREND OF KEY PLAYERS, BY PRODUCT TYPE
    AVERAGE SELLING PRICE TREND OF PRODUCT TYE, BY REGION
  • 5.11 KEY CONFERENCES & EVENTS DURING 2024-2025
  • 5.12 KEY STAKEHOLDERS & BUYING CRITERIA
    KEY STAKEHOLDERS & BUYING PROCESS
    BUYING CRITERIA
  • 5.13 UNMET NEEDS/END USER EXPECTATIONS IN DENTAL SOFT-TISSUE REGENERATION MARKET
  • 5.14 ADJACENT MARKET ANALYSIS
  • 5.15 ECOSYSTEM MARKET MAP
  • 5.16 CASE STUDY ANALYSIS
  • 5.17 SUPPLY CHAIN ANALYSIS
  • 5.18 TRENDS/DISRUPTION IMPACTING CUSTOMER’S BUSINESS
  • 5.19 INVESTMENT AND FUNDING SCENARIO
  • 5.20 REIMBURSEMENT SCENARIO
  • 5.21 IMPACT OF AI/GENAI / AI IN DENTAL SOFT-TISSUE REGENERATION MARKET
DENTAL SOFT-TISSUE REGENERATION MARKET, BY PRODUCT TYPE, 2023-2030 (USD MILLION)
113
  • 6.1 INTRODUCTION
  • 6.2 AUTOGRAFTS
  • 6.3 SYNTHETIC BIOMATERIALS
  • 6.4 COLLAGEN-BASED MEMBRANES
  • 6.5 OTHERS
DENTAL SOFT-TISSUE REGENERATION MARKET, BY APPLICATION, 2023-2030 (USD MILLION)
145
  • 7.1 INTRODUCTION
  • 7.2 IMPLANTOLOGY
  • 7.3 PERIODONTOLOGY
  • 7.4 OTHERS
DENTAL SOFT-TISSUE REGENERATION MARKET, BY END USER, 2023-2030 (USD MILLION)
198
  • 8.1 INTRODUCTION
  • 8.2 DENTAL HOSPITALS
  • 8.3 DSO’S & INDEPENDENT CLINICS
  • 8.4 ACADEMIC & RESEARCH INSTITUTIONS
DENTAL SOFT-TISSUE REGENERATION MARKET, BY REGION, 2023-2030 (USD MILLION)
250
  • 9.1 INTRODUCTION
  • 9.2 NORTH AMERICA
    MACROECONOMIC OUTLOOK FOR NORTH AMERICA
    US
    CANADA
  • 9.3 EUROPE
    MACROECONOMIC OUTLOOK FOR EUROPE
    GERMANY
    UK
    FRANCE
    SPAIN
    ITALY
    REST OF EUROPE
  • 9.4 ASIA PACIFIC
    MACROECONOMIC OUTLOOK FOR ASIA PACIFIC
    JAPAN
    CHINA
    INDIA
    AUSTRALIA
    SOUTH KOREA
    REST OF ASIA PACIFIC
  • 9.5 LATIN AMERICA
    MACROECONOMIC OUTLOOK FOR LATIN AMERICA
    BRAZIL
    MEXICO
    ARGENTINA
    REST OF LATIN AMERICA
  • 9.6 MIDDLE EAST & AFRICA
    MACROECONOMIC OUTLOOK FOR MIDDLE EAST & AFRICA
  • 9.7 GCC COUNTRIES
    MACROECONOMIC OUTLOOK FOR GCC COUNTRIES
COMPETITIVE LANDSCAPE
267
  • 10.1 OVERVIEW
  • 10.2 KEY PLAYER STRATEGIES/RIGHT TO WIN
  • 10.3 REVENUE SHARE ANALYSIS OF KEY PLAYERS , 2021-2023
  • 10.4 MARKET SHARE ANALYSIS, 2023
  • 10.5 COMPANY EVALUATION MATRIX: KEY PLAYERS, 2024
    STARS
    EMERGING LEADERS
    PERVASIVE PLAYERS
    PARTICIPANTS
    COMPANY FOOTPRINT: KEY PLAYERS, 2024
    - COMPANY FOOTPRINT
    - REGION FOOTPRINT
    - PRODUCT TYPE FOOTPRINT
    - APPLICATION FOOTPRINT
    - END USER FOOTPRINT
  • 10.6 COMPANY EVALUATION MATRIX: START-UPS/SMES, 2024
    PROGRESSIVE COMPANIES
    RESPONSIVE COMPANIES
    DYNAMIC COMPANIES
    STARTING BLOCKS
    COMPETITIVE BENCHMARKING: START-UPS/SMES, 2024
    - DETAILED LIST OF KEY START-UPS/SMES
    - COMPETITIVE BENCHMARKING OF START-UPS/SMES
  • 10.7 COMPETITIVE SITUATION AND TRENDS
    PRODUCT LAUNCHES
    DEALS
    EXPANSIONS
    OTHER DEVELOPMENTS
  • 10.8 DENTAL SOFT-TISSUE REGENERATION MARKET, BRAND/PRODUCT COMPARATIVE ANALYSIS
  • 10.9 R&D ASSESSMENT OF KEY PLAYERS
  • 10.10 VALUATION AND FINANCIAL METRICS OF KEY PLAYERS IN DENTAL SOFT-TISSUE REGENERATION MARKET
COMPANY PROFILES
287
  • 11.1 KEY PLAYERS
    GEISTLICH PHARMA AG
    DENTSPLY SIRONA
    INSTITUT STRAUMANN AG
    ZIMVIE INC.
    HENRY SCHEIN, INC.
    ABBVIE INC.
    ADVANCED MEDICAL SOLUTIONS GROUP PLC
    TISSUE REGENIX
    SEPTODONT HOLDING
    MEDICAL CONSULT IMPLANTS GMBH
    MECCELLIS
    REGEDENT AG
    REGENITY
    ENVISTA
    AD SURGICAL
  • 11.2 OTHER PLAYERS
    LIFENET HEALTH, INC.
    B&B DENTAL IMPLANT COMPANY
    ALPHA-BIO TEC. LTD.
    LASAK S.R.O.
    KEYSTONEDENTALGROUP
    NEOSS AG
    BEGO GMBH & CO. KG
    BERKELEY ADVANCED BIOMATERIALS
    SAMYANG HOLDINGS CORPORATION
    RTI SURGICAL
APPENDIX
303
  • 12.1 INSIGHTS OF INDUSTRY EXPERTS
  • 12.2 DISCUSSION GUIDE
  • 12.3 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL
  • 12.4 AVAILABLE CUSTOMIZATION
  • 12.5 RELATED REPORTS
  • 12.6 AUTHOR DETAILS

This study involved four key activities to estimate the current size of the dental soft-tissue regeneration market. First, extensive secondary research was conducted to gather information about the market, as well as related markets and the overall parent market. Next, the findings, assumptions, and estimates were validated through primary research conducted with industry experts across the value chain. Both top-down and bottom-up approaches were utilized to determine the overall market size. Finally, market breakdown and data triangulation techniques were employed to estimate the sizes of various segments and subsegments.

Secondary Research

The secondary research process utilized a variety of sources, including directories and databases such as Bloomberg Business, Factiva, and D&B Hoovers, as well as white papers, annual reports, company documents, investor presentations, and SEC filings. This method was employed to gather information relevant to a comprehensive, technical, market-focused, and commercial analysis of the dental soft-tissue regeneration market. It also helped obtain crucial details about key players in the industry, market classification, and segmentation based on current trends, extending down to the most granular levels. Additionally, important developments related to market and technological perspectives were captured. A database of key industry leaders was created using the information collected through secondary research.

Primary Research

In the primary research process, a variety of sources from both the supply and demand sides were interviewed to gather qualitative and quantitative information for this report. On the supply side, primary sources included industry experts such as CEOs, vice presidents, marketing and sales directors, technology and innovation directors, and other key executives from important companies and organizations operating in the dental soft-tissue regeneration market. On the demand side, primary sources consisted of industry experts, purchasing and sales managers, doctors, and personnel from research organizations. This primary research aimed to validate market segmentation, identify key players, and collect insights on major industry trends and market dynamics.

A breakdown of the primary respondents for the dental soft-tissue regeneration market is provided below:

Dental Soft-tissue Regeneration Market

Note 1: C-level executives include CEOs, CFOs, COOs, and VPs.

Note 2: Others include sales managers, marketing managers, business development managers, product managers, distributors, and suppliers.

Note 3: Companies are classified into tiers based on their total revenue. As of 2024, Tier 1 = >USD 10.00 billion, Tier 2 = USD 1.00 billion to USD 10.00 billion, and Tier 3 = < USD 1.00 billion.

Source: MarketsandMarkets Analysis

To know about the assumptions considered for the study, download the pdf brochure

Market Size Estimation

For the global market value, annual revenues were calculated based on the revenue mapping of major product manufacturers and OEMs active in the global dental soft-tissue regeneration market. All the major product manufacturers were identified at the global and/or country/regional level. Revenue mapping for the respective business segments/sub-segments was done for the major players. Also, the global dental soft-tissue regeneration market was split into various segments and subsegments based on:

  • List of major players operating in the products market at the regional and/or country level
  • Product mapping of various dental soft-tissue regeneration manufacturers at the regional and/or country level
  • Mapping of annual revenue generated by listed major players from dental soft-tissue regenerative products (or the nearest reported business unit/product category)
  • Revenue mapping of major players to cover at least 70–75% of the global market share as of 2023
  • Extrapolation of the revenue mapping of the listed major players to derive the global market value of the respective segments/subsegments
  • Summation of the market value of all segments/subsegments to arrive at the global diagnostics market

The above-mentioned data was consolidated and added with detailed inputs and analysis from MarketsandMarkets and presented in this report.

Market Size Estimation (Bottom-up Approach & Top-down Approach)

Dental Soft-tissue Regeneration Market

Data Triangulation

After arriving at the overall size of the global dental soft-tissue regeneration market through the above-mentioned methodology, this market was split into several segments and subsegments. Where applicable, the data triangulation and market breakdown procedures were employed to complete the overall market engineering process and arrive at the exact market value data for the key segments and subsegments. The extrapolated market data was triangulated by studying various macroindicators and regional trends from both demand- and supply-side participants.

Market Definition

Dental soft-tissue regeneration involves restoring or reconstructing soft tissues, including the gums and connective tissues surrounding the teeth. This process seeks to facilitate the healing of tissues lost due to gum disease or trauma to enhance the health and aesthetic appearance of the gums and their functionality. These procedures can be effectively used in the treatment of gum recession, tissue defects around the implants, or any other soft-tissue defects, and eventually, to improve the smile.

Stakeholders

  • Dental soft-tissue regenerative material manufacturing companies
  • Distributors and suppliers of dental soft-tissue regeneration products
  • Medical device companies
  • Research and consulting firms
  • Healthcare institutions (hospitals, laboratories, medical schools, and outpatient clinics)
  • Research institutes and academic centers
  • Contract research organizations (CROs)
  • Government associations
  • Venture capitalists and investors

Report Objectives

  • To define, describe, and forecast the dental soft-tissue regeneration market based on product type, application, end user, and region
  • To forecast the market size based on six key regions: North America, Europe, Asia Pacific, Latin America, the Middle East & Africa, and GCC Countries
  • To strategically analyze the industry trends, technology trends, pricing analysis, regulatory scenario, supply/value chain, ecosystem mapping, Porter’s five forces, patent analysis, key stakeholders and buying criteria, and conference and events
  • To provide detailed information regarding the major factors influencing the growth of this market (such as drivers, restraints, opportunities, and challenges)
  • To analyze the micromarkets with respect to individual growth trends, prospects, and contributions to the overall dental soft-tissue regeneration market
  • To analyze the opportunities for stakeholders and provide details of the competitive landscape for market leaders
  • To strategically profile key players in the dental soft-tissue regeneration market and comprehensively analyze their core competencies
  • To track and analyze competitive developments such as product launches & approvals, partnerships, agreements, collaborations, joint ventures, expansions, and acquisitions in the overall dental soft-tissue regeneration market
  • To benchmark players within the market using the proprietary “Company Evaluation Matrix” framework, which analyzes market players on various parameters within the broad categories of business and product/service strategy
  • To analyze the generative AI impact on the dental soft-tissue regeneration market

Previous Versions of this Report

Dental Soft-Tissue Regeneration Market by Product Type (Autografts, Synthetic Biomaterials, Collagen-based Membranes), Application (Implantology, Periodontology), End User (Dental Hospitals, DSO's & Independent Clinics), Region - Global Forecast to 2029

Report Code MD 9222
Published in Nov, 2024, By MarketsandMarkets™
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